Trairak Pisitkun
Chulalongkorn University Systems Biology (CUSB), Thailand
Title: Integrated design of antibodies for systems biology using AbDesigner
Biography
Biography: Trairak Pisitkun
Abstract
In the current era of large-scale biology, systems biology has evolved as a powerful approach to identify complex interactions within biological systems. In addition to high throughput identification and quantification techniques, methods based on high-quality mono-specific antibodies remain an essential element of the approach. To assist the large-scale design and production of peptide-directed antibodies for systems biology studies, we developed a fully integrated online application, AbDesigner to help researchers select optimal peptide immunogens for antibody generation against relatively disordered regions of target proteins. Here we describe AbDesigner in terms of its features, comparing it to other software tools, and the applications of it to design various antibodies.
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